vort3

I’d say the stopping thing is a few multiplayer PvP games with anticheat, also some software that won’t work in Wine (adobe products, corel products, microsoft products). Yes, I know alternatives exist (Krita, Inkscape, LibreOffice). No, they are not 100% drop-in replacements. I for myself love working in LibreOffice Writer, but when you work in a place where everyone except you uses MS Word and expects DOCX files, you can’t “just” switch to linux without issue.

Others have already explained about PDF not being easy to edit and lack of FOSS tools. The only advice I can give is that PDF XChange editor works well under Wine if you have it.